The differential diagnosis of crystals in the retina

被引:34
作者
Nadim F. [1 ]
Walid H. [1 ]
Adib J. [1 ]
机构
[1] Deparment of Ophthalmology, American University of Beirut, Medical Center, Beirut
关键词
Bietti; Cystinosis; Differential; Drug toxicity; Oxalosis; Retinal crystals;
D O I
10.1023/A:1021189215498
中图分类号
学科分类号
摘要
Crystalline deposits in the retina may be associated with a wide variety of systemic disorders such as oxalosis, cystinosis, hyperornithinaemia and Sjögren-Larsson syndrome. Refractile crystalline deposits may also be a manifestation of drug toxicity like the antineoplastic agent tamoxifen, the anesthetic methoxyflurane and the oral tanning agent canthaxanthine. Crystals may also occur in drug abusers who inject multiple crushed tablets of methadone or meperidine intravenously (talc retinopathy). The differential diagnosis of retinal crystals also includes primary ocular diseases like Biettis crystalline retinopathy, calcified macular drusen, idiopathic parafoveal telangiectasis and longstanding retinal detachment. This article will review the most common causes of crystalline retinopathies, their etiologies, pathologies and clinical characteristics.
引用
收藏
页码:113 / 121
页数:8
相关论文
共 60 条
[1]  
Bullock J.D., Albert D.M., Flecked retina appearance secondary to oxalate crystals from methoxyflurane anesthesia, Archives of Ophth, 93, pp. 26-31, (1975)
[2]  
Farrel J., Shoemaker J.D., Otti T., Jordan W., Schoch L., Neu L.T., Bastani B., Primary hyperoxaluria in an adult with renal failure, livedo reticularis, retinopathy and peripheral neuropathy, American Journal of Kidney Diseases, 29, pp. 947-952, (1997)
[3]  
Wells C., Johnson R., Qingli L., Bunt-Milam A., Kalina R.E., Retinal oxalosis
[4]  
A clinicopathologic report, Arch Ophthalmol, 107, pp. 1638-1643, (1989)
[5]  
Bullock J.D., Albert D.M., Skinner C.W., Miller W.H., Galla J.H., Calcium oxalate retinopathy associated with generalized oxalosis: X-ray diffraction and electron microscopic studies of deposits, Investigative Ophthalmology, 13, pp. 256-265, (1974)
[6]  
Town M., Jean G., Cherqui S., Attard M., Forestier L., Whitmore S.A., Callen D.F., Et al., A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis, Nat Genet, 18, 4, pp. 319-324, (1998)
[7]  
Adamson M.D., Andersson H.C., Gahl W.A., Cystinosis, Semin Nephrol, 9, pp. 147-161, (1989)
[8]  
Offner G., Latta K., Hoyer P.F., Baum H., Ehrich J.H., Pichlmayr R., Brodehl J., Kidney transplanted children come of age, Kidney International, 55, pp. 1509-1517, (1999)
[9]  
Demetrios S., Theodoropoulos, Krasnewich D., Kaiser-Kupfer M.I., Gahl W., Classic nephropathic cystinosis as an adult disease, JAMA, 270, pp. 2200-2204, (1993)
[10]  
Read J., Goldberg M.F., Fishman G., Rosenthal I., Nephropathic cystinosis, American J Ophth, 76, pp. 791-796, (1973)