CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala

被引：0

作者：

Yu Zhou

Jaejoon Won

Mikael Guzman Karlsson

Miou Zhou

Thomas Rogerson

Jayaprakash Balaji

Rachael Neve

Panayiota Poirazi

Alcino J Silva

机构：

[1] University of California Los Angeles,Department of Neurobiology

[2] Semel Institute,Department of Psychology

[3] University of California Los Angeles,undefined

[4] University of California Los Angeles,undefined

[5] Brain Research Institute,undefined

[6] University of California Los Angeles,undefined

[7] Picower Institute,undefined

[8] Massachusetts Institute of Technology,undefined

[9] Computational Biology Laboratory,undefined

[10] Institute of Molecular Biology and Biotechnology (IMBB),undefined

[11] Foundation of Research and Technology Hellas,undefined

[12] Vassilika Vouton,undefined

[13] Present address: Department of Physiology,undefined

[14] Medical College of Qingdao University,undefined

[15] Qingdao,undefined

[16] China.,undefined

来源：

Nature Neuroscience | 2009年 / 12卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Silva et al. show that CREB modulates allocation of fear memory to specific cells in the lateral amygdala. Reversibly inactivating a subset of CREB-expressing neurons disrupted memory for tone conditioning. Neurons with higher CREB levels were more excitable than their neighbors and showed larger synaptic efficacy changes following tone conditioning.

引用

页码：1438 / 1443

页数：5

共 50 条

[1] CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala
Zhou, Yu
Won, Jaejoon
Karlsson, Mikael Guzman
Zhou, Miou
Rogerson, Thomas
Balaji, Jayaprakash
Neve, Rachael
Poirazi, Panayiota
Silva, Alcino J.
NATURE NEUROSCIENCE, 2009, 12 (11) : 1438 - 1443
[2] CREB regulates spine density of lateral amygdala neurons: implications for memory allocation
Sargin, Derya
Mercaldo, Valentina
Yiu, Adelaide P.
Higgs, Gemma
Han, Jin-Hee
Frankland, Paul W.
Josselyn, Sheena A.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 2013, 7
[3] CREB Regulates Memory Allocation in the Insular Cortex
Sano, Yoshitake
Shobe, Justin L.
Zhou, Miou
Huang, Shan
Shuman, Tristan
Cai, Denise J.
Golshani, Peyman
Kamata, Masakazu
Silva, Alcino J.
CURRENT BIOLOGY, 2014, 24 (23) : 2833 - 2837
[4] Enhanced CREB-dependent gene expression increases the excitability of neurons in the basal amygdala and primes the consolidation of contextual and cued fear memory
Viosca, Jose
Lopez de Armentia, Mikel
Jancic, Dragana
Barco, Angel
LEARNING & MEMORY, 2009, 16 (03) : 193 - 197
[5] CREB modulates excitability of nucleus accumbens neurons
Yan Dong
Thomas Green
Daniel Saal
Helene Marie
Rachael Neve
Eric J Nestler
Robert C Malenka
Nature Neuroscience, 2006, 9 : 475 - 477
[6] CREB modulates excitability of nucleus accumbens neurons
Dong, Y
Green, T
Saal, D
Marie, H
Neve, R
Nestler, EJ
Malenka, RC
NATURE NEUROSCIENCE, 2006, 9 (04) : 475 - 477
[7] SEROTONERGIC MODULATION ON THE EXCITABILITY OF LATERAL AMYGDALA NEURONS
Yamamoto, Ryo
Sugai, Tokio
Ueta, Yoshifumi
Kato, Nobuo
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, 59 : 288 - 288
[8] Dopamine modulates excitability of basolateral amygdala neurons in vitro
Kröner, S
Rosenkranz, JA
Grace, AA
Barrionuevo, G
JOURNAL OF NEUROPHYSIOLOGY, 2005, 93 (03) : 1598 - 1610
[9] Glucocorticoids enhance the excitability of principal basolateral amygdala neurons
Duvarci, Sevil
Pare, Denis
JOURNAL OF NEUROSCIENCE, 2007, 27 (16): : 4482 - 4491
[10] Neurons Are Recruited to an Amygdala Fear Memory Trace Based on Relative Neuronal Excitability Immediately Before Training
Josselyn, Sheena
NEUROPSYCHOPHARMACOLOGY, 2014, 39 : S106 - S107

← 1 2 3 4 5 →