Synthesis of highly congested α-amino acids and peptides

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Nature Synthesis | 2022年 / 1卷
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A method for the synthesis of sterically congested α-amino acids and peptides using amino acid Schiff bases and hydrocarbons is developed. A superior helix-stabilizing effect of highly congested unnatural α-amino acids is demonstrated by circular dichroism measurements of synthesized peptides.
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页码:269 / 270
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