Inherited and experimentally induced changes in gating kinetics of muscle nicotinic acetylcholine receptor

被引:0
作者
Cecilia Bouzat
Francisco J. Barrantes
机构
[1] Universidad Nacional del Sur-CONICET,Instituto Investigaciones Bioquímicas
来源
Journal of Molecular Neuroscience | 1999年 / 13卷
关键词
Nicotinic; gating kinetics; pathology; channelopathies; genetic disorders;
D O I
暂无
中图分类号
学科分类号
摘要
Ligand-gated ion channels (LGIC) allow rapid responses in the nervous system. The nicotonic acetylcholine receptor (AChR) has been the model for structure-function relationship studies on this superfamily. The AChR undergoes the following functional events:Binding of the neurotransmitter.Opening of the ion channel.Conduction of ions across the pore.Desensitization.
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页码:1 / 16
页数:15
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