Modification of biologically active amides and amines with fluorine-containing heterocycles 4. Trifluoromethyl-containing heterocyclic pyracetam derivatives

被引：0
作者：
V. B. Sokolov
A. Yu. Aksinenko
T. A. Epishina
T. V. Goreva
机构：
[1] Russian Academy of Sciences,Institute of Physiologically Active Compounds
来源：
Russian Chemical Bulletin | 2010年 / 59卷
关键词：
pyracetam; hexafluoroacetone; 3-aminocrotononitrile; 6-aminouracyls; 6-amino-1-phenylthiouracyl; -benzyl-3-aminocyclohexenone; 2-aminothiazoline; fluorine-containing compounds; 1,4-dihydropyrimidine; dihydropyrimido[4,5-; ]pyrimidines; tetrahydro-1; -quinazoline; thiazolo[3,2-; ][1,3,5]triazine; cyclocondensation.;
D O I：
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学科分类号：
摘要：
A one-pot method for the synthesis of trifluoromethyl-containing heterocyclic pyracetam derivatives has been suggested by the reaction of pyracetam, hexafluoroacetone, and 1,3-binucleophiles, viz., 3-aminocrotononitrile, 6-aminouracyls, 6-aminothiouracyl, N-benzyl-3-aminocyclohexenone, and 2-aminothiazoline.
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页码：864 / 866
页数：2
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