Comparison of GP IIB/IIIA Inhibitors and Their Activity as Measured by Aggregometry, Flow Cytometry, Single Platelet Counting, and the Rapid Platelet Function Analyzer

被引：0
作者：
Axel C. Matzdorff
Gitta Kühnel
Bettina Kemkes-Matthes
Reinhard Voss
机构：
[1] Justus-Liebig-University,Department of Hematology/Oncology, (Chair: Prof. Dr. H. Pralle), Ctr. for Internal Medicine
来源：
Journal of Thrombosis and Thrombolysis | 2001年 / 12卷
关键词：
GP IIb/IIIa-inhibitor; aggregometry; Rapid Platelet Function Analyzer; flow cytometry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: GP IIb/IIIa inhibitors have primarily been used short-term e.g., during PTCA. They failed to show clinical benefit during long-term therapy. One reason might be the absence of a method to monitor inhibitor activity. This study compared platelet aggregometry, the rapid platelet function analyzer (RPFA) test, single platelet counting, and flow cytometric determination of receptor occupancy to measure GP IIb/IIIa-receptor inhibitor activity.
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页码：129 / 139
页数：10
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