Myocardial Inflammation—Are We There Yet?

被引：53

作者：

Greulich S. ^{[1
]}

Ferreira V.M. ^{[2
]}

Dall’Armellina E. ^{[2
]}

Mahrholdt H. ^{[1
]}

机构：

[1] Division of Cardiology, Robert Bosch Medical Center, Auerbachstrasse 110, Stuttgart

[2] Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Headington, Oxford

来源：

Current Cardiovascular Imaging Reports | 2015年 / 8卷 / 3期

关键词：

Cardiovascular magnetic resonance; Edema; Gadolinium; Mapping; Myocardial inflammation; Tissue characterization;

D O I：

10.1007/s12410-015-9320-6

中图分类号：

学科分类号：

摘要：

Several exogenous or endogenous factors can lead to inflammatory heart disease. Beside infectious myocarditis, other systemic inflammatory disorders such as sarcoidosis, systemic lupus erythematosus (SLE), systemic sclerosis (SSc), Churg-Strauss syndrome, and rheumatoid arthritis can affect the myocardium. Myocardial inflammation may have a major impact on the outcome of these patients, resulting in sudden cardiac death, severe arrhythmias, or end-stage heart failure. The current gold standard for definite confirmation of inflammatory heart disease is endomyocardial biopsy (EMB), but is invasive and suffers low sensitivity and specificity due to sampling errors. Thus, non-invasive methods for detecting the extent and changes over time of the inflammatory myocardial disease are needed. Cardiac magnetic resonance (CMR) is such a non-invasive method. We will describe and discuss different approaches for CMR assessment of inflammatory myocardial disease including early gadolinium enhancement (EGE), T2-weighted imaging, late gadolinium enhancement (LGE), the newer mapping proton relaxation techniques (T1 pre-contrast, T1 post-contrast, T2 mapping), and the hybrid PET/MRI technique. © 2015, The Author(s).

引用

页数：11

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