Successful treatment of radiation cystitis with hyperbaric oxygen therapy: Resolution of bleeding event and changes of histopathological findings of the bladder mucosa
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作者:
Suzuki K.
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Department of Urology, Gunma University, School of Medicine, Maebashi, GunmaDepartment of Urology, Gunma University, School of Medicine, Maebashi, Gunma
Suzuki K.
[1
]
Kurokawa K.
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Department of Urology, Gunma University, School of Medicine, Maebashi, GunmaDepartment of Urology, Gunma University, School of Medicine, Maebashi, Gunma
Kurokawa K.
[1
]
Suzuki T.
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机构:
Department of Urology, Gunma University, School of Medicine, Maebashi, GunmaDepartment of Urology, Gunma University, School of Medicine, Maebashi, Gunma
Suzuki T.
[1
]
Okazaki H.
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机构:
Department of Urology, Gunma University, School of Medicine, Maebashi, GunmaDepartment of Urology, Gunma University, School of Medicine, Maebashi, Gunma
Okazaki H.
[1
]
Otake N.
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Department of Urology, Gunma University, School of Medicine, Maebashi, GunmaDepartment of Urology, Gunma University, School of Medicine, Maebashi, Gunma
Otake N.
[1
]
Imai K.
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Department of Urology, Gunma University, School of Medicine, Maebashi, GunmaDepartment of Urology, Gunma University, School of Medicine, Maebashi, Gunma
Imai K.
[1
]
Yamanaka H.
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Department of Urology, Gunma University, School of Medicine, Maebashi, GunmaDepartment of Urology, Gunma University, School of Medicine, Maebashi, Gunma
Yamanaka H.
[1
]
机构:
[1] Department of Urology, Gunma University, School of Medicine, Maebashi, Gunma
Cystitis;
Tranexamic Acid;
Hyperbaric Oxygen;
International Urology;
Submucosal Layer;
D O I:
10.1007/BF02550308
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学科分类号:
摘要:
To assess the effect of hyperbaric oxygen (HBO) therapy on radiation cystitis, clinical and histopathological characteristics were examined. Three women with radiation cystitis were treated with HBO therapy. Macrohaematuria was arrested in all patients. Cystoscopy demonstrated abnormal telangiectasia and inflammatory mucosa before treatment. After HBO therapy, the inflammatory mucosae were healed. However, abnormal vessels did not completely disappear. Histopathologically, the epithelium was atrophic and dilated lymph vessels and inflammatory cells were seen in the submucosa. These changes improved after treatment. HBO therapy is effective against radiation cystitis. With improvement of the clinical symptoms also the cystoscopic and histopathological findings changed favourably.