Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses

被引:0
作者
Maximiliano J. Spetter
Enrique L. Louge Uriarte
Andrea E. Verna
Anselmo C. Odeón
Erika A. González Altamiranda
机构
[1] Universidad Nacional del Centro de la Provincia de Buenos Aires,Centro de Investigación Veterinaria de Tandil (CIVETAN) CONICET
[2] Paraje Arroyo Seco S/N,CICPBA
[3] Campus Universitario,UNCPBA, Facultad de Ciencias Veterinarias
[4] Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS,Laboratorio de Virología Veterinaria
[5] INTA-CONICET),Facultad de Ciencias Agrarias
[6] Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET),undefined
[7] Universidad Nacional de Mar del Plata,undefined
来源
Brazilian Journal of Microbiology | 2023年 / 54卷
关键词
BVDV; Virus evolution; Phylodynamic;
D O I
暂无
中图分类号
学科分类号
摘要
Bovine viral diarrhea virus (BVDV) genome consists of a single-stranded, positive-sense RNA with high genetic diversity. In the last years, significant progress has been achieved in BVDV knowledge evolution through phylodynamic analysis based on the partial 5′UTR sequences, whereas a few studies have used other genes or the complete coding sequence (CDS). However, no research has evaluated and compared BVDV evolutionary history based on the complete genome (CG), CDS, and individual genes. In this study, phylodynamic analyses were carried out with BVDV-1 (Pestivirus A) and BVDV-2 (Pestivirus B) CG sequences available on the GenBank database and each genomic region: CDS, UTRs, and individual genes. In comparison to the CG, the estimations for both BVDV species varied according to the dataset used, pointing out the importance of considering the analyzed genomic region when concluding. This study may provide new insight into BVDV evolution history while highlighting the need to increase the available BVDV CG sequences to perform more comprehensive phylodynamic studies in the future.
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页码:2461 / 2469
页数:8
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