Immunoliposomes Directed Toward VCAM-1 Interact Specifically with Activated Endothelial Cells—A Potential Tool for Specific Drug Delivery

被引:0
作者
Manuela Voinea
Ileana Manduteanu
Elena Dragomir
Monica Capraru
Maya Simionescu
机构
[1] Institute of Cellular Biology and Pathology,
[2] Military Hospital “Dr. D. Gerota”,undefined
来源
Pharmaceutical Research | 2005年 / 22卷
关键词
binding; endothelial cells; liposomes; uptake; VCAM-1;
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学科分类号
摘要
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页码:1906 / 1917
页数:11
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[1]  
Bevilacqua M. P.(1987)Inducible endothelial functions in inflammation and coagulation Semin. Thromb. Hemost. 13 425-433
[2]  
Pober J. S.(1995)Adhesion molecules: a new target for immunoliposome-mediated drug delivery FEBS Lett. 357 140-144
[3]  
Mendrick D. L.(2003) cellular handling and Pharm. Res. 20 64-72
[4]  
Cotran R. S.(1998) targeting of E-selectin-directed immunoconjugates and immunoliposomes used for drug delivery to inflamed endothelium Pharm. Acta Helv. 73 19-26
[5]  
Gimbrone M. A.(1999)Selectins as new targets for immunoliposome-mediated drug delivery. A potential way of anti-inflammatory therapy Biochim. Biophys. Acta 1419 353-363
[6]  
Bloemen P. G. M.(2001)Cellular uptake of liposomes targeted to intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelial cells Biochim. Biophys. Acta 1514 177-190
[7]  
Henricks P. A. J.(2001)Investigation of the cellular uptake of E-selectin-targeted immunoliposomes by activated human endothelial cells J. Clin. Invest. 107 1255-1262
[8]  
van Bloois L.(1992)A major role for VCAM-1, but nor ICAM-1, in early atherosclerosis J. Biol. Chem. 267 8366-8370
[9]  
van den Tweel M. C.(1992)Adhesion to vascular cell adhesion molecule 1 and fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpfa4 beta 7 on human T cell line JY J. Cell Biol. 117 179-189
[10]  
Bloem A. C.(1995)Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering Adv. Immunol. 58 345-416