Flavones with free radical scavenging activity fromGoniothalamus tenuifolius

被引：0
作者：
Kittisak Likhitwitayawuid
Chaweewan Klongsiriwet
Vichien Jongbunprasert
Boonchoo Sritularak
Samphan Wongseripipatana
机构：
[1] Chulalongkom University,Department of Pharmacognosy, Faculty of Pharmaceutical Sciences
[2] Chulalongkom University,Department of Pharmaceutical Botany, Faculty of Pharmaceutical Sciences
来源：
Archives of Pharmacal Research | 2006年 / 29卷
关键词：
flavone; free radical scavenging activity; DPPH;
D O I：
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学科分类号：
摘要：
From the leaves ofGoniothalamus tenuifolius, a new natural product namely 3′-hydroxy-3,5,7,4′-tetramethoxyflavone (1) was isolated, along with seven other known compounds (2–8). Each of these isolates was evaluated for free radical scavenging activity on the DPPH decoloration test. The data obtained in this study suggested that theortho 3′,4′-diphenolic structure was essential for the activity of these flavonol derivatives.
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页码：199 / 202
页数：3
相关论文
共 80 条
[1]  
Beutler J. A.(1998)Structure-activity requirements for flavone cytotoxicity and binding to tubulin J. Med. Chem. 41 2333-2338
[2]  
Hamel E.(2002)Hemisynthesis of all the Tetrahedron 58 10001-10009
[3]  
Vlietinch A. J.(2002)-monomethylated analogues of quercetin including the major metabolites, through selective protection of phenolic functions J. Ethnopharmacology 79 379-381
[4]  
Haemers A.(1999)Antioxidant activity of flavonoids from Phytochemistry 50 899-902
[5]  
Rajan P.(2001)Eicosenones and methylated flavonols from Spectrochim. Acta Part A 57 513-519
[6]  
Roitman J. N.(1987)A comparative vibrational and NMR study of Yakugaku Zasshi 107 954-958
[7]  
Cardellina J. H.(1981)-cinnamic acid polymorphs and Chem. Pharm. Bull. 29 254-256
[8]  
Boyd M. R.(1997)-cinnamic acid Pharm. Pharmacol. Lett. 7 99-102
[9]  
Bouktaib M.(1999)Flavonoid constituents of J. Wood. Sci. 45 53-63
[10]  
Lebrun S.(1996) Merr Indian J. Chem. 35B 220-232
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