Effects of beauvericin to mammalian tissue and its production by Austrian isolates of Fusarium proliferatum and Fusarium subglutinans

被引：14
作者：
Krska R. [1 ]
Schuhmacher R. [1 ]
Grasserbauer M. [1 ]
Lemmens M. [1 ]
Lemmens-Gruber R. [2 ]
Adler A. [3 ]
Lew H. [3 ]
机构：
[1] Institute for Agrobiotechnology (IFA), Center for Analytical Chemistry, Laboratory of Plant Production Biotechnology, Konrad Lorenz Str. 20
[2] Institute of Pharmacology and Toxicology, University of Vienna, Althansstr. 14
[3] Federal Office of Agrobiology, Wieningerstr. 8
来源：
Mycotoxin Research | 1997年 / 13卷 / 1期
关键词：
Fusarium Species; Mycotoxin Research; Fusarium Moniliforme; Austrian Isolate; Beauvericin;
D O I：
10.1007/BF02945057
中图分类号：
学科分类号：
摘要：
Austrian isolates of Fusarium subglutinans and Fusarium proliferatum were studied for their ability to produce beauvericin, moniliformin and fumonisin B1 and B2 under laboratory conditions. Analytical methodology for beauvericin was specially adapted for this task. Our analyses showed that the strains produced beauvericin up to 687 mg/kg maize and moniliformin up to 70 mg/kg. The culture of F. proliferatum in addition produced fumonisin B1 and B2 at levels of 106 and 61 mg/kg, respectively. The preliminary toxicity experiments performed in this study clearly indicated a toxic effect of beauvericin on the contractility of mammalian smooth muscle and thus on mammalian cells.
引用
收藏
页码：11 / 16
页数：5
相关论文
共 29 条
  • [1] Nirenberg, H.I., (1996) Personal Communication
  • [2] Chelkowski, J., Mycotoxins associated with corn cob fusariosis (1989) Fusarium: Mycotoxins, Taxonomy and Pathogenicity, pp. 53-62. , In: Chelkowsky J (Ed) Elsevier Science Publishers BV, Amsterdam
  • [3] Lew, H., Adler, A., Edinger, W., Moniliformin and the european corn borer (ostrinia nubilalis) (1991) Mycotox Res, 7 A, pp. 71-76
  • [4] Chelkowsky, J., Zawadzki, M., Zajkowski, P., Logrieco, A., Bottalico, A., Moniliformin production by fusarium species (1990) Mycotox Res, 6, pp. 41-45
  • [5] Kriek, N.P.J., Marasas, W.F.O., Steyn, P.S., Rensburg, S.J., Steyan, M., Toxicity of moniliformin-producing strain offusarium moniliforme vat. Subglutinans isolated from maize (1977) Food Cosmet Toxicol, 15, pp. 579-585
  • [6] Burmeister, H.R., Ciegler, A., Vesonder, R.F., Moniliformin, a metabolite of fusarium moniliforme nrrl 6322: Purification and toxicity (1979) Appl Environ Microbio, 137, pp. 11-13
  • [7] Gupta, S., Krasnoff, S.B., Underwood, N.L., Renwick, J.A.A., Roberts, D.W., Isolation of beauvericin as an insect toxin from fusarium semitectum and fusarium monilnwle var. Subglutinans (1991) Mycopathologia, 115, pp. 185-189
  • [8] Logrieco, A., Moretti, A., Altomare, C., Bottalico, A., Carbonell Torres, E., Occurrence and toxicity of fusarium sttbglutinatts from peruvian maize (1993) Mycopathologia, 102, pp. 185-190
  • [9] Logrieco, A., Moretti, A., Ritieni, A., Chelkowski, J., Altomare, C., Bottalico, A., Randazzo, G., Natural occurrence of beauvericin in preharvest fusarium subglutinans infected corn ears in poland (1993) J Agric Food Chem, 41, pp. 2149-2152
  • [10] Moretti, A., Logrieco, A., Bottalico, A., Ritieni, A., Randazzo, G., Production of beauvericin by fusaritmzproliferatum from maize in italy (1994) Mycotox Res, 10, pp. 73-78
123