A Patient with Psoriasis and Vitiligo Treated with Etanercept

被引：0

作者：

Anna Campanati

Katia Giuliodori

Giulia Ganzetti

Giulia Liberati

Anna Maria Offidani

机构：

[1] Polytechnic Marche University,Dermatological Clinic, Medical and Biotatistics Science Department

来源：

American Journal of Clinical Dermatology | 2010年 / 11卷

关键词：

Psoriasis; Etanercept; Vitiligo; Dermatology Life Quality Index; Psoriatic Lesion;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Psoriasis is a chronic, immune-mediated, inflammatory dermatosis whose aetiopathogenesis remains unclear, although tumour necrosis factor alpha (TNFα) appears to play a crucial role. The biological potential of TNFα inhibitors, such as etanercept, which reduce the inflammatory cascade, has radically changed the therapeutic management of patients with psoriasis and other immunomediated inflammatory diseases, associated with TNFα. The pathogenesis of the selective destruction of melanocytes in vitiligo is not fully understood, although there is growing evidence that several T helper type 1 cytokines, particularly TNFα, may be involved in the depigmentation process.

引用

页码：46 / 48

页数：2

共 26 条

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