Detection and Molecular Characterization of Yellow Fever Virus, 2017, Brazil

被引：0

作者：

P. O. Figueiredo

A. T. S. Silva

J. S. Oliveira

P. E. Marinho

F. T. Rocha

G. P. Domingos

P. C. P. Poblete

L. B. S. Oliveira

D. C. Duarte

C. A. Bonjardim

J. S. Abrahão

E G. Kroon

B. P. Drumond

D. B. Oliveira

G. S. Trindade

机构：

[1] Universidade Federal de Minas Gerais,Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas

[2] Universidade Federal dos Vales do Jequitinhonha e Mucuri,Centro Integrado de Pesquisa em Saúde, Faculdade de Medicina

[3] Zoovet Consultoria LTDA,undefined

[4] Pontifical Catholic University of Minas Gerais,undefined

来源：

EcoHealth | 2018年 / 15卷

关键词：

Non-human primates; Emerging infectious diseases; Zoonotic virus; Arboviruses; Outbreak;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

At the end of 2016, Brazil experienced an unprecedented yellow fever (YF) outbreak. Clinical, molecular and ecological aspects of human and non-human primate (NHP) samples collected at the beginning of the outbreak are described in this study. Spatial distribution analyses demonstrated a strong overlap between human and NHP cases. Through molecular analyses, we showed that the outbreak had a sylvatic origin, caused by the South American genotype 1 YFV, which has already been shown to circulate in Brazil. As expected, the clusters of cases were identified in regions with a low vaccination coverage. Our findings highlight the importance of the synchronization of animal surveillance and health services to identify emerging YF cases, thereby promoting a better response to the vulnerable population.

引用

页码：864 / 870

页数：6

共 145 条

[1]

Barbosa CM(2018)Yellow fever virus in urine and semen of convalescent patient, Brazil Emerging Infectious Diseases 52 209-229

[2]

Di Paola N(2007)Yellow fever: a disease that has yet to be conquered Annual Review of Entomology 112 447-451

[3]

Cunha MP(2017)Genome analysis of yellow fever virus of the ongoing outbreak in Brazil reveals polymorphisms Memórias do Instituto Oswaldo Cruz 13 198-210

[4]

Rodrigues-Jesus MJ(2013)Evolutionary and ecological factors underlying the tempo and distribution of yellow fever virus activity Infection, Genetics and Evolution 2 11-26

[5]

Araujo DB(2011)Evolução histórica da vigilância epidemiológica e do controle da febre amarela no Brasil Revista Pan-Amazônica de Saúde 74 68-76

[6]

Silveira VB(2012)Yellow fever outbreak affecting Alouatta populations in southern Brazil (Rio Grande do Sul State), 2008–2009 American Journal of Primatology 43 696-702

[7]

Oliveira DBL(2005)Duplex reverse transcription-PCR followed by nested PCR assays for detection and identification of Brazilian alphaviruses and flaviviruses Journal of Clinical Microbiology 42 58-64

[8]

Barrett AD(2008)Rapid routine detection of enterovirus RNA in cerebrospinal fluid by a one-step real-time RT-PCR assay Journal of Clinical Virology 8 e3295-2041

[9]

Higgs S(2014)Pathophysiologic and transcriptomic analyses of viscerotropic yellow fever in a rhesus macaque model PLOS Neglected Tropical Diseases 23 2038-321

[10]

Bonaldo MC(2017)Outbreak of yellow fever among nonhuman primates, Espirito Santo, Brazil, 2017 Emerging Infectious Diseases 59 307-120

← 1 2 3 4 5 6 7 8 9 10 →