Practical Evidence-Based Recommendations for Patients with Multiple Sclerosis Who Want to Have Children

被引:0
作者
Yara Dadalti Fragoso
Tarso Adoni
Joseph B. Bidin Brooks
Alessandro Finkelsztejn
Paulo Diniz da Gama
Anderson K. Grzesiuk
Vanessa Daccach Marques
Monica Fiuza K. Parolin
Henry K. Sato
Daniel Lima Varela
Claudia Cristina F. Vasconcelos
机构
[1] Universidade Metropolitana de Santos,
[2] Hospital Sirio-Libanes de Sao Paulo,undefined
[3] Hospital de Clinicas de Porto Alegre,undefined
[4] Pontificia Universidade Católica Campus Sorocaba,undefined
[5] Neurologic Clinic in Cuiaba,undefined
[6] Universidade de Sao Paulo Campus Ribeirao Preto,undefined
[7] Neurologic Clinic in Curitiba,undefined
[8] Instituto de Neurologia de Curitiba,undefined
[9] Servico de Neurologia e Neurocirurgia,undefined
[10] Universidade Federal do Estado do Rio de Janeiro,undefined
来源
Neurology and Therapy | 2018年 / 7卷
关键词
Family planning; Multiple sclerosis; Neurology; Pregnancy; Therapy;
D O I
暂无
中图分类号
学科分类号
摘要
Multiple sclerosis (MS) management presently aims to reach a state of no (or minimal) evidence of disease activity. The development and commercialization of new drugs has led to a renewed interest in family planning, since patients with MS may face a future with reduced (or no) disease-related neurological disability. The advice of neurologists is often sought by patients who want to have children and need to know more about disease control at conception and during pregnancy and the puerperium. When MS is well controlled, the simple withdrawal of drugs for patients who intend to conceive is not an option. On the other hand, not all treatments presently recommended for MS are considered safe during conception, pregnancy and/or breastfeeding. The objective of the present study was to summarize the practical and evidence-based recommendations for family planning when our patients (women and men) have MS.
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页码:207 / 232
页数:25
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  • [1] Doshi A(2017)Multiple sclerosis, a treatable disease Clin Med (Lond) 17 530-536
  • [2] Chataway J(2017)“No evident disease activity”: the use of combined assessments in the management of patients with multiple sclerosis Mult Scler 23 1179-1187
  • [3] Giovannoni G(2015)Multiple sclerosis and pregnancy in the ‘treatment era’ Nat Rev Neurol 11 280-289
  • [4] Tomic D(1999)Developing clinical guidelines West J Med 170 348-351
  • [5] Bright JR(2014)Postpartum relapses increase the risk of disability progression in multiple sclerosis: the role of disease modifying drugs J Neurol Neurosurg Psychiatry 85 845-850
  • [6] Vukusic S(2014)Predictors and dynamics of postpartum relapses in women with multiple sclerosis Mult Scler 20 739-746
  • [7] Marignier R(2017)Management of pregnancy-related issues in multiple sclerosis patients: the need for an interdisciplinary approach Neurol Sci 38 1849-1858
  • [8] Shekelle PG(2011)Vitamin D, pregnancy, breastfeeding and postpartum multiple sclerosis relapses Arch Neurol 68 310-313
  • [9] Woolf SH(2015)The influence of vitamin D on postpartum relapse and quality of life in pregnant multiple sclerosis patients Eur J Neurol 22 479-484
  • [10] Eccles M(2017)Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials BMJ 359 j5237-395