Initial Real-Life Experience from a Designated COVID-19 Centre in Athens, Greece: a Proposed Therapeutic Algorithm

被引:17
作者
Ioannis G. Baraboutis
Panagiotis Gargalianos
Eleni Aggelonidou
Andreas Adraktas
机构
[1] Pammakaristos Hospital of Divine Providence (Reference Centre for COVID-19 Infection),Internal Medicine Clinic
[2] Athens Medical Centre/Athens Medical Group,Internal Medicine and Infectious Diseases Department, Hellenic Society for Infectious Diseases
关键词
COVID-19 infection; Coinfections; Bovine coronavirus; Ferritin; C-reactive protein; D-dimer; Viral replication; Human immunodeficiency virus (HIV); Pneumocystis jiroveci pneumonia; Oral candidiasis; Adult respiratory distress syndrome; Cytokine release syndrome; Immunomodulatory therapy; Interleukin-6; Interleukin-1; Soluble urokinase-type plasminogen activator receptor; Antimicrobial therapy; Corticosteroids; Lung microbiota;
D O I
10.1007/s42399-020-00324-x
中图分类号
学科分类号
摘要
We report our initial experience with the management of a mixed group of patients with COVID-19 infection, admitted and treated in a designated COVID-19 centre in the Athens Metropolitan area over a 4-week period. The SARS-CoV-2 pandemic presented a huge challenge to the Greek National Healthcare System and healthcare workers. Their response so far has been miraculously effective. Since there are essentially no therapeutic guidelines yet for this disease, we relied mainly on our medical intuition, our empathy for our patients and team work to do the best possible for 49 people with this infection. We present the therapeutic algorithm we gradually developed (on the job) and applied in our patients, based on continuous creative brainstorming and monitoring of the literature.
引用
收藏
页码:689 / 693
页数:4
相关论文
共 58 条
[1]  
Saif LJ(2010)Bovine respiratory coronavirus Vet Clin North Am Food Anim Pract 26 349-364
[2]  
Sodhi M(2020)Therapeutic potential for tetracyclines in the treatment of COVID-19 Pharmacotherapy. 40 487-488
[3]  
Etminan M(2020)Teicoplanin: an alternative drug for the treatment of COVID-19? Int J Antimicrob Agents 13 105944-929
[4]  
Baron SA(2020)Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics Diabetes Metab Res Rev 31 e33213321-402
[5]  
Devaux C(2020)Tigecycline interferes with fibrinogen polymerization independent of peripheral interactions with the coagulation system Antibiotics (Basel) 9 E84-2
[6]  
Colson P(1987)Trimethoprim-sulfamethoxazole Mayo Clin Proc 62 921-420
[7]  
Raoult D(2020)COVID-19: combining antiviral and anti-inflammatory treatments Lancet Infect Dis 20 400-690
[8]  
Rolain JM(2020)Involving antimicrobial stewardship programs in COVID-19 response efforts: all hands on deck Infect Control Hosp Epidemiol 13 1-undefined
[9]  
Maddaloni E(2019)Commentary: Early clinical indicators of Addison’s disease in adults with type 1 diabetes: a nationwide, observational, cohort study Front Endocrinol (Lausanne) 10 456-undefined
[10]  
Buzzetti R(2020)Corticosteroid treatment of patients with coronavirus disease 2019 (COVID-19) Med J Aust 212 416-undefined