Protective effects of zinc on cadmium toxicity in rodents

被引：0
|
作者：
C. Claverie
R. Corbella
D. Martín
C. Díaz
机构：
[1] University of La Laguna,Department of Analytical Chemistry, Nutrition and Food Science
[2] University of La Laguna,Department of Physical Medicine and Pharmacology
来源：
Biological Trace Element Research | 2000年 / 75卷
关键词：
Cadmium; cadmium toxicity; zinc; zinc-protective effect; accumulation factors; biochemical parameters;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A study of acute and subacute toxicity of cadmium ions [Cd(II)] was carried out on male Swiss mice and Sprague-Dawley rats with and without previous administration of zinc chloride. The LD50 of Cd(II) as cadmium sulfate (ip) was lower in animals previously given 10 mg/kg of zinc(II) chloride (sc). Factors such as animal weight variations, biochemical parameters, and accumulation patterns of Cd(II) and Zn(II) were taken into consideration when the subacute toxicity was evaluated.
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页码：1 / 9
页数：8
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