Patients with mantle-cell lymphoma relapsing after autologous stem cell transplantation may be rescued by allogeneic transplantation

被引：0

作者：

C Martínez

E Carreras

M Rovira

Á Urbano-Ispizua

J Esteve

M Perales

F Fernández

E Montserrat

机构：

[1] Institute of Hematology and Oncology,Department of Hematology

[2] Transplantation Unit,undefined

[3] Postgraduate School of Hematology ‘Farreras-Valentí’,undefined

[4] IDIBAPS,undefined

[5] Hospital Clínic,undefined

[6] University of Barcelona,undefined

来源：

Bone Marrow Transplantation | 2000年 / 26卷

关键词：

mantle-cell lymphoma; allogeneic stem cell transplantation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Two patients with disseminated mantle-cell lymphoma relapsed 24 and 13 months, respectively, after high-dose chemotherapy and autologous stem cell transplantation (autoSCT). Both patients had an HLA-identical sibling and received an allogeneic stem cell transplant (alloSCT) 32 and 18 months after autologous transplant, after conditioning with fractionated 12 Gy total body irradiation plus cyclophosphamide 120 mg/kg. They are both alive and in complete remission 24 months after transplant. Both patients have developed chronic graft-versus-host disease and their Karnofsky performance status is 90%. AlloSCT may offer a useful approach in a subgroup of patients with mantle-cell lymphoma who have relapsed after autologous transplantation. Bone Marrow Transplantation (2000) 26, 677–679.

引用

页码：677 / 679

页数：2

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