Patients with mantle-cell lymphoma relapsing after autologous stem cell transplantation may be rescued by allogeneic transplantation

被引：0
|
作者：
C Martínez
E Carreras
M Rovira
Á Urbano-Ispizua
J Esteve
M Perales
F Fernández
E Montserrat
机构：
[1] Institute of Hematology and Oncology,Department of Hematology
[2] Transplantation Unit,undefined
[3] Postgraduate School of Hematology ‘Farreras-Valentí’,undefined
[4] IDIBAPS,undefined
[5] Hospital Clínic,undefined
[6] University of Barcelona,undefined
来源：
Bone Marrow Transplantation | 2000年 / 26卷
关键词：
mantle-cell lymphoma; allogeneic stem cell transplantation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two patients with disseminated mantle-cell lymphoma relapsed 24 and 13 months, respectively, after high-dose chemotherapy and autologous stem cell transplantation (autoSCT). Both patients had an HLA-identical sibling and received an allogeneic stem cell transplant (alloSCT) 32 and 18 months after autologous transplant, after conditioning with fractionated 12 Gy total body irradiation plus cyclophosphamide 120 mg/kg. They are both alive and in complete remission 24 months after transplant. Both patients have developed chronic graft-versus-host disease and their Karnofsky performance status is 90%. AlloSCT may offer a useful approach in a subgroup of patients with mantle-cell lymphoma who have relapsed after autologous transplantation. Bone Marrow Transplantation (2000) 26, 677–679.
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页码：677 / 679
页数：2
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