Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

被引：0
作者：
Takashi Satoh
Hiroyasu Kidoya
Hisamichi Naito
Masahiro Yamamoto
Naoki Takemura
Katsuhiro Nakagawa
Yoshichika Yoshioka
Eiichi Morii
Nobuyuki Takakura
Osamu Takeuchi
Shizuo Akira
机构：
[1] Laboratory of Host Defense,Department of Host Defense
[2] WPI Immunology Frontier Research Center (WPI IFReC),Department of Signal Transduction
[3] Osaka University,Department of Immunoparasitology
[4] 3-1 Yamada-oka,Department of Pathology
[5] Suita,undefined
[6] Osaka 565-0871,undefined
[7] Japan ,undefined
[8] Research Institute for Microbial Diseases (RIMD),undefined
[9] Osaka University,undefined
[10] 3-1 Yamada-oka,undefined
[11] Suita,undefined
[12] Osaka 565-0871,undefined
[13] Japan,undefined
[14] Research Institute for Microbial Diseases (RIMD),undefined
[15] Osaka University,undefined
[16] 3-1 Yamada-oka,undefined
[17] Suita,undefined
[18] Osaka 565-0871,undefined
[19] Japan,undefined
[20] Laboratory of immunoparasitology,undefined
[21] WPI Immunology Frontier Research Center (WPI IFReC),undefined
[22] Osaka University,undefined
[23] 3-1 Yamada-oka,undefined
[24] Suita,undefined
[25] Osaka 565-0871,undefined
[26] Japan ,undefined
[27] Research Institute for Microbial Diseases (RIMD),undefined
[28] Osaka University,undefined
[29] 3-1 Yamada-oka,undefined
[30] Suita,undefined
[31] Osaka 565-0871,undefined
[32] Japan,undefined
[33] Laboratory of Biofunctional Imaging,undefined
[34] WPI Immunology Frontier Research Center (WPI IFReC),undefined
[35] Osaka University,undefined
[36] 3-1 Yamada-oka,undefined
[37] Suita,undefined
[38] Osaka 565-0871,undefined
[39] Japan ,undefined
[40] Graduate School of Medicine,undefined
[41] Osaka University,undefined
[42] 2-2 Yamada-oka,undefined
[43] Suita,undefined
[44] Osaka 565-0871,undefined
[45] Japan,undefined
[46] Laboratory of Infection and Prevention,undefined
[47] Institute for Virus Research,undefined
[48] Kyoto University,undefined
[49] 53 Shogoin Kawara-cho,undefined
[50] Sakyo-ku,undefined
来源：
Nature | 2013年 / 495卷
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学科分类号：
摘要：
Haematopoietic expression of the adaptor protein Trib1 is shown to be required for the presence of adipose-tissue-resident macrophages with an M2-like phenotype; Trib1 deficiency leads to aberrant expression of C/EBPα and impaired adipose tissue function.
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页码：524 / 528
页数：4
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