Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

被引：0

作者：

Takashi Satoh

Hiroyasu Kidoya

Hisamichi Naito

Masahiro Yamamoto

Naoki Takemura

Katsuhiro Nakagawa

Yoshichika Yoshioka

Eiichi Morii

Nobuyuki Takakura

Osamu Takeuchi

Shizuo Akira

机构：

[1] Laboratory of Host Defense,Department of Host Defense

[2] WPI Immunology Frontier Research Center (WPI IFReC),Department of Signal Transduction

[3] Osaka University,Department of Immunoparasitology

[4] 3-1 Yamada-oka,Department of Pathology

[5] Suita,undefined

[6] Osaka 565-0871,undefined

[7] Japan ,undefined

[8] Research Institute for Microbial Diseases (RIMD),undefined

[9] Osaka University,undefined

[10] 3-1 Yamada-oka,undefined

[11] Suita,undefined

[12] Osaka 565-0871,undefined

[13] Japan,undefined

[14] Research Institute for Microbial Diseases (RIMD),undefined

[15] Osaka University,undefined

[16] 3-1 Yamada-oka,undefined

[17] Suita,undefined

[18] Osaka 565-0871,undefined

[19] Japan,undefined

[20] Laboratory of immunoparasitology,undefined

[21] WPI Immunology Frontier Research Center (WPI IFReC),undefined

[22] Osaka University,undefined

[23] 3-1 Yamada-oka,undefined

[24] Suita,undefined

[25] Osaka 565-0871,undefined

[26] Japan ,undefined

[27] Research Institute for Microbial Diseases (RIMD),undefined

[28] Osaka University,undefined

[29] 3-1 Yamada-oka,undefined

[30] Suita,undefined

[31] Osaka 565-0871,undefined

[32] Japan,undefined

[33] Laboratory of Biofunctional Imaging,undefined

[34] WPI Immunology Frontier Research Center (WPI IFReC),undefined

[35] Osaka University,undefined

[36] 3-1 Yamada-oka,undefined

[37] Suita,undefined

[38] Osaka 565-0871,undefined

[39] Japan ,undefined

[40] Graduate School of Medicine,undefined

[41] Osaka University,undefined

[42] 2-2 Yamada-oka,undefined

[43] Suita,undefined

[44] Osaka 565-0871,undefined

[45] Japan,undefined

[46] Laboratory of Infection and Prevention,undefined

[47] Institute for Virus Research,undefined

[48] Kyoto University,undefined

[49] 53 Shogoin Kawara-cho,undefined

[50] Sakyo-ku,undefined

来源：

Nature | 2013年 / 495卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

Haematopoietic expression of the adaptor protein Trib1 is shown to be required for the presence of adipose-tissue-resident macrophages with an M2-like phenotype; Trib1 deficiency leads to aberrant expression of C/EBPα and impaired adipose tissue function.

引用

页码：524 / 528

页数：4

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