Two New Benzoquinone Derivatives and Two New Bisorbicillinoids were Isolated from a Marine-derived Fungus Penicillium terrestre

被引：0

作者：

Weizhong Liu

Qianqun Gu

Weiming Zhu

Chengbin Cui

Guotao Fan

机构：

[1] Key Laboratory of Marine Drugs,

[2] Chinese Ministry of Education,undefined

[3] Institute of Marine Drugs and Food,undefined

[4] Ocean University of China,undefined

[5] Beijing Institute of Pharmacology and Toxicology,undefined

[6] AMMS,undefined

来源：

The Journal of Antibiotics | 2005年 / 58卷

关键词：

benzoquinone; bisorbicillinoids; dihydrobisvertinolone; Tetrahydrobisvertinolone; cytotoxic activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Four new compounds were isolated from a marine-derived fungus Penicillium terrestre, namely 2-(2′, 3′-dihydrosorbyl)-3,6-dimethyl-5-hydroxy-1,4-benzoquinone (1), 3-acetonyl-2,6-dimethyl-5-hydroxy-1,4-benzoquinone (2), dihydrobisvertinolone (3), tetrahydrobisvertinolone (4). Their structures were established on the basis of spectroscopic methods. The absolute configurations of 3 and 4 were determined by their CD spectra. Their cytotoxic effects on P388 and A-549 cell lines were preliminarily examined by the MTT method.

引用

页码：441 / 446

页数：5