Reactions of 3,3-dialkyl-2,3-dihydro-6-trifluoromethyl-4-pyrones with hydroxylamine. Synthesis and structures of 5-(1,1-dialkyl-2-hydroxyethyl)-5-hydroxy-3-trifluoromethyl-Δ2-isoxazolines

被引：0
作者：
V. Ya. Sosnovskikh
M. Yu. Mel'nikov
S. A. Pogozhikh
机构：
[1] A. M. Gorky Ural State University,A. N. Nesmeyanov Institute of Organoelement Compounds
[2] Russian Academy of Sciences,undefined
来源：
Russian Chemical Bulletin | 1999年 / 48卷
关键词：
CF; -containing 2,3-dihydro-4-pyrones; hydroxylamine; (hydroxyalkyl)-enaminones; regioisomeric Δ; X-ray diffraction analysis;
D O I：
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学科分类号：
摘要：
The reactions of 3,3-dialkyl-2,3-dihydro-6-trifluoromethyl-4-pyrones with hydroxylamine hydrochloride afforded regioisomeric 3(5)-(1,1-dialkyl-2-hydroxyethyl)-5-hydroxy-5(3)-trifluoromethyl-Δ2-isoxazolines depending on the reaction conditions. The title compounds were also prepared from 2,2-dialkyl-5-amino-1-hydroxy-6,6,6-trifluorohex-4-en-3-ones. The above dihydropyrones reacted with hydroxylamine (base) to yield 3-(1,1-dialkyl-2-hydroxyethyl)-5-hydroxy-5-trifluoromethyl-Δ2-isoxazolines.
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页码：1323 / 1328
页数：5
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