Numerical investigation of novel 2D photonic structure for cancerous cell detection

In this paper, we proposed a novel Swastik photonic sensor (SPS) to detect cancerous cells using human blood samples. The proposed structure has sharp bends at the corner of central rods by introducing line and point defects to achieve better interaction of light with the analytes. The analytes such as Basal, HeLa, Jurkat, PC-12, MDA-MB-231, and MCF-7 are placed individually at the center of the Swastik structure and electric field distribution has been analyzed at ports 1, 2, and 3. We have only obtained a linear relationship between electric field intensity and analytes refractive index at port 2 and calculated all the sensing parameters at the same port using the finite difference time domain (FDTD) method. We have observed the highest sensitivity of 3648.214 nm/RIU at the resonance wavelength of 1566.173 nm for MCF-7 cancerous cells, whereas the highest quality factor (Q) and figure of merit (FoM) is obtained for Jurkat cancerous cell at 1522.189 nm. The highest limit of detection (LoD) and signal-to-noise ratio (SNR) have been achieved at resonance wavelengths of 1505.745 nm and 1524.568 nm, respectively, for Basal and HeLa cancerous cells. We have compared all our calculated values with the available results in the literature.