Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers

被引:0
作者
Andre F. Batista
Tayná Rody
Leticia Forny-Germano
Suzana Cerdeiro
Maria Bellio
Sergio T. Ferreira
Douglas P. Munoz
Fernanda G. De Felice
机构
[1] Federal University of Rio de Janeiro,Institute of Medical Biochemistry Leopoldo de Meis
[2] Federal University of Rio de Janeiro,Department of Immunology, Institute of Microbiology Paulo de Góes
[3] Federal University of Rio de Janeiro,Institute of Biophysics Carlos Chagas Filho
[4] Queen’s University,Centre for Neuroscience Studies
[5] Queen’s University,Department of Psychiatry
来源
Journal of Neuroinflammation | / 18卷
关键词
Alzheimer’s disease; Mitochondrial dynamics; Mitochondrial dysfunction; IL-1β; Neuroinflammation; Aβ oligomers;
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  • [1] Masters CL(2015)Alzheimer's disease Nat Rev Dis Primers. 1 15056-608
  • [2] Bateman R(2016)The amyloid hypothesis of Alzheimer's disease at 25 years EMBO Mol Med. 8 595-3911
  • [3] Blennow K(2006)Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons EMBO J. 25 3900-117
  • [4] Rowe CC(2017)Slower dynamics and aged mitochondria in sporadic Alzheimer's disease Oxid Med Cell Longev. 2017 9302761-335
  • [5] Sperling RA(2016)Mitochondrial dynamics and metabolic regulation Trends Endocrinol Metab. 27 105-1086
  • [6] Cummings JL(2013)Why size matters - balancing mitochondrial dynamics in Alzheimer's disease Trends Neurosci. 36 325-84
  • [7] Selkoe DJ(2017)Mitochondrial dysfunction and synaptic transmission failure in Alzheimer's disease J Alzheimers Dis. 57 1071-18675
  • [8] Hardy J(2019)Spatially stable mitochondrial compartments fuel local translation during plasticity Cell. 176 73-2547
  • [9] Barsoum MJ(2010)Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model Proc Natl Acad Sci U S A. 107 18670-9103
  • [10] Yuan H(2012)Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage Hum Mol Genet. 21 2538-5110