Apoptotic and antioxidant effects in HCT-116 colorectal carcinoma cells by a spiro-acridine compound, AMTAC-06

被引:0
作者
Sâmia Sousa Duarte
Daiana Karla Frade Silva
Thaís Mangeon Honorato Lisboa
Rawny Galdino Gouveia
Camyla Caroliny Neves de Andrade
Valgrícia Matias de Sousa
Rafael Carlos Ferreira
Ricardo Olimpio de Moura
Joilly Nilce Santana Gomes
Patricia Mirella da Silva
Fátima de Lourdes Assunção Araújo de Azevedo
Tatjana S. L. Keesen
Juan Carlos Ramos Gonçalves
Leônia Maria Batista
Marianna Vieira Sobral
机构
[1] Federal University of Paraíba,Postgraduation Program in Bioactive Natural and Synthetic Products
[2] State University of Paraíba,Drug Development and Synthesis Laboratory, Department of Pharmacy
[3] Federal University of Paraíba,Invertebrate Immunology and Pathology Laboratory, Department of Molecular Biology
[4] Federal University of Paraíba,Cardiovascular Pharmacology Laboratory, Postgraduation Program in Bioactive Natural and Synthetic Products
[5] Federal University of Paraíba,Immunology of Infectious Diseases Laboratory, Biotechnology Center
[6] Federal University of Paraíba,Department of Pharmaceutical Sciences
[7] Instituto de Pesquisa em Fármacos e Medicamentos (IPeFarM). Cidade Universitária,Laboratório de Oncofarmacologia (Oncofar)
来源
Pharmacological Reports | 2022年 / 74卷
关键词
Spiro-acridine; Antioxidant action; Antitumor activity; Cell cycle; Apoptosis; Colorectal cancer;
D O I
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中图分类号
学科分类号
摘要
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页码:545 / 554
页数:9
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[1]  
Hanahan D(2011)Hallmarks of cancer: the next generation Cell 144 646-674
[2]  
Weinberg RA(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424
[3]  
Bray F(2018)Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors Bioorg Med Chem 26 3958-3966
[4]  
Ferlay J(2017)How much longer will we put up With $100,000 cancer drugs? Cell 168 579-583
[5]  
Soerjomataram I(2017)Principles of chemotherapy and radiotherapy Obstet Gynaecol Reprod Med 27 206-212
[6]  
Siegel RL(2019)A view on drug resistance in cancer Nature 575 299-309
[7]  
Torre LA(2021)Anticancer drugs approved by the US food and drug administration from 2009 to 2020 according to their mechanism of action JAMA Netw Open 4 3-9
[8]  
Jemal A(2012)Acridine: a versatile heterocyclic nucleus Acta Pol Pharm 69 15776-15804
[9]  
Chen J(2017)Recent developments in the synthesis and biological activity of acridine/acridone analogues RSC Adv 7 1-15
[10]  
Li D(2019)Design, synthesis, antimicrobial, and anticancer activities of acridine thiosemicarbazides derivatives Molecules 24 467-475