Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss

被引：0
作者：
Michael X. Hernandez
Shan Jiang
Tracy A. Cole
Shu-Hui Chu
Maria I. Fonseca
Melody J. Fang
Lindsay A. Hohsfield
Maria D. Torres
Kim N. Green
Rick A. Wetsel
Ali Mortazavi
Andrea J. Tenner
机构：
[1] University of California,Department of Pathology and Laboratory Medicine, School of Medicine
[2] University of California,Department of Developmental and Cell Biology
[3] University of California,Department of Neurobiology and Behavior
[4] University of California,Department of Molecular Biology and Biochemistry
[5] University of Texas-Houston,Research Center for Immunology and Autoimmune Diseases, Institute of Molecular Medicine for the Prevention of Human Diseases
[6] Present Address: Ionis Pharmaceuticals Inc.,undefined
来源：
Molecular Neurodegeneration | / 12卷
关键词：
C5a; C5a receptor; Alzheimer’s disease; Complement; Microglia; Mouse models; Behavior; Gene expression; Inflammation; Phagosome;
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