An M2e-based synthetic peptide vaccine for influenza A virus confers heterosubtypic protection from lethal virus challenge

[1] Cox RJ(2004)Influenza Virus: Immunity and Vaccination Strategies. Comparison of the Immune Response to Inactivated and Live, Attenuated Influenza Vaccines Scand J Immunol 59 1365-3083

[2] Brokstad KA(2005)Universal influenza A vaccine: Optimization of M2-based constructs Virology 337 149-161

[3] Ogra P(2009)Emergence and pandemic potential of swine-origin H1N1 influenza virus Nature 459 931-939

[4] De Filette M(2009)Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans Science 2009 197-201

[5] Willy MJ(1992)Evolution and ecology of influenza A viruses Microbiol Rev 56 152-179

[6] Birkett A(1980)Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75 Nature 286 771-776

[7] Lyons K(1988)A novel method for producing anti-peptide antibodies. Production of site-specific antibodies to the T cell antigen receptor beta-chain J Biol Chem 263 1719-1725

[8] Schultz B(1988)Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system Proc Natl Acad Sci USA 85 5409-5413

[9] Tonkyro A(2005)Influenza type A virus escape mutants emerge in vivo in the presence of antibodies to the ectodomain of matrix protein 2 J Virol 79 6644-6654

[10] Resch S(2011)Vaccination with M2e-Based Multiple Antigenic Peptides: Characterization of the B Cell Response and Protection Efficacy in Inbred and Outbred Mice PLoS One 6 e28445-7

[1] Cox RJ(2004)Influenza Virus: Immunity and Vaccination Strategies. Comparison of the Immune Response to Inactivated and Live, Attenuated Influenza Vaccines Scand J Immunol 59 1365-3083

[2] Brokstad KA(2005)Universal influenza A vaccine: Optimization of M2-based constructs Virology 337 149-161

[3] Ogra P(2009)Emergence and pandemic potential of swine-origin H1N1 influenza virus Nature 459 931-939

[4] De Filette M(2009)Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans Science 2009 197-201

[5] Willy MJ(1992)Evolution and ecology of influenza A viruses Microbiol Rev 56 152-179

[6] Birkett A(1980)Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75 Nature 286 771-776

[7] Lyons K(1988)A novel method for producing anti-peptide antibodies. Production of site-specific antibodies to the T cell antigen receptor beta-chain J Biol Chem 263 1719-1725

[8] Schultz B(1988)Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system Proc Natl Acad Sci USA 85 5409-5413

[9] Tonkyro A(2005)Influenza type A virus escape mutants emerge in vivo in the presence of antibodies to the ectodomain of matrix protein 2 J Virol 79 6644-6654

[10] Resch S(2011)Vaccination with M2e-Based Multiple Antigenic Peptides: Characterization of the B Cell Response and Protection Efficacy in Inbred and Outbred Mice PLoS One 6 e28445-7