Cognitive assessment in asymptomatic COVID-19 subjects

被引：63

作者：

Amalakanti S. ^{[1
]}

Arepalli K.V.R. ^{[2
]}

Jillella J.P. ^{[3
]}

机构：

[1] Institute of Bioinformatics, Discoverer Building, 7th Floor, International Tech Park, Whitefield, Bengaluru

[2] Department of General Medicine, Great Eastern Medical School and Hospital, Ragolu

[3] GNM, Harika College of Physiotherapy, Guntur

来源：

VirusDisease | 2021年 / 32卷 / 1期

关键词：

COVID-19; brain; cognition; neurological; neuropsychiatric; psychiatric;

D O I：

10.1007/s13337-021-00663-w

中图分类号：

学科分类号：

摘要：

Neurological features of COVID-19 have been reported in addition to the respiratory manifestations, but cognitive dysfunction has been scarcely described. And cognitive assessment has not been studied in asymptomatic subjects. We compared the cognitive assessment scores between asymptomatic SARS-CoV-2 infected subjects with that of controls to detect mild cognitive impairment by the Montreal Cognitive Assessment test. Asymptomatic COVID-19 subjects secured lower scores in certain domains of the MoCA in comparison with the controls. The domains were visuoperception (2.4 ± 0.7 vs2.8 ± 0.7, p = 0.032), naming (3.6 ± 0.5 vs3.9 ± 0.2, p = 0.016) and fluency (0.9 ± 0.6 vs1.6 ± 0.7, p = < 0.001). Also, older aged COVID-19 positive subjects scored lower in the MoCA when compared to the younger people. Our study shows that even otherwise asymptomatic COVID-19 subjects have cognitive deficits in certain subdomains and suggests the need for a detailed psychometric assessment especially in the elderly population. © 2021, Indian Virological Society.

引用

页码：146 / 149

页数：3

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