A simpler rat kidney transplantation model: A variation in arterial anastomotic technique

被引：1
作者：
Ilie V. [1 ]
Ilie V. [1 ]
Wang C. [2 ]
Bishop A. [2 ]
机构：
[1] Department of Transplantation Surgery, Royal Prince Alfred Hospital, Sydney
[2] Collaborative Transplantation Group, University of Sydney, Sydney
来源：
European Journal of Plastic Surgery | 2013年 / 36卷 / 6期
关键词：
Kidney transplant; Microsurgery; Telescoping artery;
D O I：
10.1007/s00238-013-0823-6
中图分类号：
学科分类号：
摘要：
Background: The rat kidney transplant (KTx) became a classic experimental model for training purposes in general microsurgical techniques. We present a modified version of the arterial 'sleeve' (telescoping) anastomotic technique. Methods: A cohort of rat kidney transplants executed with this modified anastomotic technique was audited for execution times, long-term graft survival and complications. Results: The series comprises 70 KTx carried out by one microsurgeon. The average warm ischaemic time was 25.75 ± 3.8 min, with an arterial anastomotic time of 10.82 ± 3.85 min. It decreased to less than 30 min (cut-off for long-term graft damage) after nine transplants. The long-term survival rate was 94.3 %, with no complication in the surviving group; the deaths were due to haemorrhage (1.42 %) and ureteric dehiscence (4.28 %). Conclusions: Telescoping the renal artery delivers good results with a faster, less laborious technique, making it a useful addition to the experimental surgery laboratory. By contrasting our results with reported series, we demonstrate that the model can make the rat kidney transplant accessible for a wider variety of scientists. © 2013 Springer-Verlag Berlin Heidelberg.
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页码：341 / 344
页数：3
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