Quality of life assessment of patients with chronic liver disease in eastern India using a Bengali translation chronic liver disease questionnaire

被引：18
作者：
Ray I. [1 ]
Dutta D. [1 ]
Basu P. [2 ]
De B.K. [1 ]
机构：
[1] Department of Medicine, Medical College and Hospitals Calcutta, Kolkata 700073, 88, College Street
[2] Indian Statistical Institute, Kolkata
来源：
Indian Journal of Gastroenterology | 2010年 / 29卷 / 5期
关键词：
Alcoholic liver disease; Chronic hepatitis B; Chronic hepatitis C; Quality of life; Questionnaire;
D O I：
10.1007/s12664-010-0036-x
中图分类号：
学科分类号：
摘要：
Aims: The aim of this study was to translate and validate chronic liver disease questionnaire (CLDQ) into Bengali using a standard protocol and use it to assess the impact of socioeconomic factors, etiology, disease severity and complications on the quality of life of patients. Methods: Formal translation of CLDQ to Bengali was done. Cronbach's alpha and test-retest was performed for reliability analysis. Patients with clinically stable chronic liver disease (CLD) without significant associated co-morbid states were administered Bengali CLDQ in the Liver Clinic. The clinical, biochemical and disease parameters were recorded for analysis. Results: Bengali CLDQ was administered to 100 patients with CLD. Cronbach's alpha of overall scores was 0.90 and test-retest correlation coefficient of average CLDQ was 0.86 (P < 0.001). Patients with history of decompensation (96.51 vs. 109.61; P = 0.039) and Child's C status (92.24 vs. 105.71; P = 0.028) had significantly lower CLDQ scores. CLDQ scores showed a moderate inverse correlation with Child's status (r = -0.35) and a poor correlation with MELD score (r = -0.09). Conclusion: Bengali translation of CLDQ was found to be reliable. History of decompensation, Child's C status was associated with worse CLDQ scores. Child's status may have some role in predicting quality of life of patients with CLD. MELD score had poor predictability of quality of life. © 2010 Indian Society of Gastroenterology.
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页码：187 / 195
页数：8
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