Common variants in polygenic schizophrenia

被引:0
作者
Joseph T Glessner
Hakon Hakonarson
机构
[1] The Children's Hospital of Philadelphia,Center for Applied Genomics
[2] University of Pennsylvania School of Medicine,Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia
来源
Genome Biology | / 10卷
关键词
Schizophrenia; Celiac Disease; Copy Number Variant; Polygenic Variation; Schizophrenia Case;
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学科分类号
摘要
Common variant single-nucleotide polymorphisms at the MHC locus have recently been associated with schizophrenia. Together with known associations with rare copy-number variants affecting many genes, this reveals the highly polygenic etiology of the disease.
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