Resveratrol, pterostilbene, and baicalein: plant-derived anti-biofilm agents

被引:0
作者
Irena Kolouchová
Olga Maťátková
Martina Paldrychová
Zdeněk Kodeš
Eva Kvasničková
Karel Sigler
Alena Čejková
Jan Šmidrkal
Kateřina Demnerová
Jan Masák
机构
[1] University of Chemistry and Technology,Department of Biotechnology
[2] Institute of Microbiology,Department of Diary, Fat and Cosmetic Science
[3] CAS,Department of Biochemistry and Microbiology
[4] University of Chemistry and Technology,undefined
[5] University of Chemistry and Technology,undefined
来源
Folia Microbiologica | 2018年 / 63卷
关键词
Baicalein; Resveratrol; Pterostilbene; Adhesion; Eradication; Biofilm;
D O I
暂无
中图分类号
学科分类号
摘要
Microbial adhesion to surfaces and the subsequent biofilm formation may result in contamination in food industry and in healthcare-associated infections and may significantly affect postoperative care. Some plants produce substances with antioxidant and antimicrobial properties that are able to inhibit the growth of food-borne pathogens. The aim of our study was to evaluate antimicrobial and anti-biofilm effect of baicalein, resveratrol, and pterostilbene on Candida albicans, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Escherichia coli. We determined the minimum inhibitory concentrations (MIC), the minimum adhesion inhibitory concentration (MAIC), and the minimum biofilm eradication concentration (MBEC) by crystal violet and XTT determination. Resveratrol and pterostilbene have been shown to inhibit the formation of biofilms as well as to disrupt preformed biofilms. Our results suggest that resveratrol and pterostilbene appear potentially very useful to control and inhibit biofilm contaminations by Candida albicans, Staphylococcus epidermidis, and Escherichia coli in the food industry.
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页码:261 / 272
页数:11
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