Antifungal activity of lauric acid derivatives against Aspergillus niger

The antifungal effects of lauric acid and four lauric acid derivatives (monolauroylglycerol, D-laurate A, T-laurate A, 6-O-lauroysucrose) were tested on the spore germination and the growth rate of Aspergillus niger DMF 0801. The results showed that the tested substances varied in their antifungal activity and they also confirmed the relation of the structure of tested substances and their antifungal effects. Monolauroylglycerol at concentration level between 0.2 and 1.8 mmol l–1 caused the highest inhibition of spore outgrowths whereas 6-O-lauroysucrose at concentration between 0.05 and 1.8 mmol l–1 did not exhibit inhibition of spore germination. The inhibition of colony growth rate was detected mainly at presence of 6-O-lauroysucrose.