Evaluation of blood-brain barrier transport and CNS drug metabolism in diseased and control brain after intravenous L-DOPA in a unilateral rat model of Parkinson's disease

被引：0
作者：
Paulien GM Ravenstijn
Henk-Jan Drenth
Michael J O'Neill
Meindert Danhof
Elizabeth CM de Lange
机构：
[1] LACDR Leiden University,Division of Pharmacology
[2] LAP&P Consultants BV,Neurodegenerative Diseases Drug Hunting Team
[3] Eli Lilly & Co Ltd.,LACDR/Pharmacology, Gorlaeus Laboratories
[4] Leiden University,undefined
来源：
Fluids and Barriers of the CNS | / 9卷 / 1期
关键词：
Population pharmacokinetic modelling; Parkinson's disease; rat rotenone model; BBB transport; L-DOPA; microdialysis;
D O I：
10.1186/2045-8118-9-4
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