Development of a Physiologically Based Pharmacokinetic Modelling Approach to Predict the Pharmacokinetics of Vancomycin in Critically Ill Septic Patients

Vincent JL(2006)Sepsis in European intensive care units: results of the SOAP study Crit Care Med 34 344-353

Sakr Y(2003)The epidemiology of sepsis in the United States from 1979 through 2000 N Engl J Med 348 1546-1554

Sprung CL(2007)Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003 Crit Care Med 35 1244-1250

Martin GS(1992)Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis: the ACCP/SCCM Consensus Conference Committee Chest 101 1644-1655

Mannino DM(2010)Sepsis and endothelial permeability N Engl J Med 363 689-691

Eaton S(2003)Vessel injury and capillary leak Crit Care Med 31 S502-S511

Moss M(2015)Anticoagulant modulation of inflammation in severe sepsis World J Crit Care Med. 4 105-115

Dombrovskiy VY(1993)Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture Mol Pharmacol 44 707-715

Martin AA(2000)The role of albumin in critical illness Br J Anaesth 85 599-610

Sunderram J(2013)Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012 Intensive Care Med 39 165-228

Vincent JL(2006)Sepsis in European intensive care units: results of the SOAP study Crit Care Med 34 344-353

Sakr Y(2003)The epidemiology of sepsis in the United States from 1979 through 2000 N Engl J Med 348 1546-1554

Sprung CL(2007)Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003 Crit Care Med 35 1244-1250

Martin GS(1992)Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis: the ACCP/SCCM Consensus Conference Committee Chest 101 1644-1655

Mannino DM(2010)Sepsis and endothelial permeability N Engl J Med 363 689-691

Eaton S(2003)Vessel injury and capillary leak Crit Care Med 31 S502-S511

Moss M(2015)Anticoagulant modulation of inflammation in severe sepsis World J Crit Care Med. 4 105-115

Dombrovskiy VY(1993)Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture Mol Pharmacol 44 707-715

Martin AA(2000)The role of albumin in critical illness Br J Anaesth 85 599-610

Sunderram J(2013)Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012 Intensive Care Med 39 165-228