Absolute Bioavailability of Esaxerenone and Food Effects on its Pharmacokinetics After a Single Oral Dose in Healthy Japanese Subjects: An Open-Label Crossover Study

被引:0
作者
Akifumi Kurata
Hidetoshi Furuie
Tomoko Ishizuka
Takafumi Nakatsu
Takako Shimizu
Manabu Kato
Yasuhiro Nishikawa
Hitoshi Ishizuka
机构
[1] Daiichi Sankyo Co.,Clinical Pharmacology Department
[2] Ltd.,Biostatistics and Data Management Department
[3] Medical Office,Safety and Risk Management Department
[4] Osaka Pharmacology Clinical Research Hospital,undefined
[5] Daiichi Sankyo Co.,undefined
[6] Ltd.,undefined
[7] Daiichi Sankyo Co.,undefined
[8] Ltd.,undefined
来源
Advances in Therapy | 2019年 / 36卷
关键词
Bioavailability; Drug safety; Food/herbal drug interactions; Pharmacokinetics;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1618 / 1627
页数:9
相关论文
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[1]  
Shimamoto K(2014)The Japanese Society of hypertension guidelines for the management of hypertension (JSH 2014) Hypertens Res 37 253-390
[2]  
Ando K(2003)Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure Hypertension 42 1206-1252
[3]  
Fujita T(2006)Effects of monotherapy and combination therapy on blood pressure control and target organ damage: a randomized prospective intervention study in a large population of hypertensive patients J Clin Hypertens (Greenwich) 8 634-641
[4]  
Chobanian AV(2013)2013 ESH/ESC guidelines for the management of arterial hypertension Eur Heart J 34 2159-2219
[5]  
Bakris GL(2015)The effects of aldosterone antagonists in patients with resistant hypertension: a meta-analysis of randomized and nonrandomized studies Am J Hypertens 28 1376-1385
[6]  
Black HR(2015)Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial Lancet 386 2059-2068
[7]  
Tedesco MA(2012)Mineralocorticoid receptor-associated hypertension and its organ damage: clinical relevance for resistant hypertension Am J Hypertens 25 514-523
[8]  
Natale F(2016)Resistant hypertension and the pivotal role for mineralocorticoid receptor antagonists: a clinical update 2016 Am J Med 129 661-666
[9]  
Calabro R(2016)Effects of mineralocorticoid receptor antagonists in patients with hypertension and diabetes mellitus: a systematic review and meta-analysis J Hum Hypertens 30 534-542
[10]  
Mancia G(2016)New evidence supporting the use of mineralocorticoid receptor blockers in drug-resistant hypertension Curr Hypertens Rep 18 34-273