Protective effect of hypothermia on brain neurons in rats exposed to ionizing radiation

被引：0

作者：

Gordon R.Ya. ^{[1
]}

Ignat'ev D.A. ^{[1
]}

Mel'nikova E.V. ^{[1
]}

Rogachevskii V.V. ^{[1
]}

Kraev I.V. ^{[1
]}

Khutsyan S.S. ^{[1
]}

机构：

[1] Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino

来源：

Biophysics | 2007年 / 52卷 / 3期

关键词：

Hypothermia; Hypoxia/hypercapnia; Ionizing radiation; Protein-synthesizing system;

D O I：

10.1134/S0006350907030165

中图分类号：

学科分类号：

摘要：

The protein-synthesizing system of hippocampal (CA1, CA3) and sensorimotor cortex neurons is damaged less and recovers much quicker in rats exposed to 8 Gy of γ-radiation under hypoxia/hypercapnia (body temperature 16-18°C) than under usual conditions, as evidenced by microfluorimetry and electron microscopy. The radioprotective effect does not cover the membrane structures (endoplasmic reticulum and Golgi complex), and their restoration is not so prompt. © 2007 Pleiades Publishing, Inc.

引用

页码：344 / 349

页数：5

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