Genetic polymorphism of glutathione S-transferase P1 gene and lung cancer risk

被引：0
作者：
Jordi To-Figueras
Manel Gené
Jesús Gómez-catalán
Esther Piqué
Natividad Borrego
Josep Lluís Carrasco
Josep Ramón
Jacint Corbella
机构：
[1] University of Barcelona,Toxicology Unit, IDIBAPS [Institut d'Investigacions Biomèdiques August Pi i Sunye
[2] University of Barcelona,Department of Public Health
来源：
Cancer Causes & Control | 1999年 / 10卷
关键词：
GSTM1; GSTP1; GSTT1; lung cancer; polymorphisms; susceptibility;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objectives: The human GSTTP1 gene is polymorphic with an A → G transition in exon 5 causing a replacement 105 Ile→Val in the GSTP1 protein. The two isoforms, encoded by the alleles GSTP1*A and GSTP1*B, respectively, show different catalytic efficiencies towards some carcinogenic epoxides. In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility.
引用
收藏
页码：65 / 70
页数：5
相关论文
共 50 条
  • [21] Are genetic polymorphisms of glutathione S-Transferase P1 gene associated with urothelial carcinoma of the urinary bladder?
    Rampal, Vikas
    Samuel, Benedict Paul
    Dandal, Sumita
    Kumar, Santosh
    Devasia, Antony
    Kekre, Nitin Sudhakar
    CLINICAL CANCER INVESTIGATION JOURNAL, 2019, 8 (06): : 222 - 226
  • [22] Estrogen receptor 1, Glutathione S-transferase P1, Glutathione S-transferase M1, and Glutathione S-transferase T1 Genes with Dysmenorrhea in Korean Female Adolescents
    Woo, Hee-Yeon
    Kim, Kye-Hyun
    Lim, Se-Won
    KOREAN JOURNAL OF LABORATORY MEDICINE, 2010, 30 (01): : 76 - 83
  • [23] Glutathione S-transferase P1 Ile105Val Polymorphism and Oral Cancer Risk: A Meta-Analysis
    Li, Weixing
    Chen, Jiayu
    Liu, Chibo
    INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2013, 10 (04): : 392 - 398
  • [24] Glutathione S-transferase P1, gene-gene interaction, and lung cancer susceptibility in the Chinese population: An updated meta-analysis and review
    Li, Xue-Ming
    Yu, Xiao-Wei
    Yuan, Ye
    Pu, Ming-Zhi
    Zhang, Hong-Xia
    Wang, Ke-Jian
    Han, Xu-Dong
    JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2015, 11 (03) : 565 - 570
  • [25] Genetic polymorphism of glutathione S-transferase T1 and the risk of colorectal cancer: A meta-analysis
    Wan, Hongwei
    Zhou, Yong
    Yang, Ping
    Chen, Bo
    Jia, Guiqing
    Wu, Xiaoting
    CANCER EPIDEMIOLOGY, 2010, 34 (01) : 66 - 72
  • [26] An updated meta-analysis of the relationship between glutathione S-transferase T1 null/presence gene polymorphism and the risk of lung cancer
    Liu, Tao
    Liu, Wen-Zhou
    Sun, Yu
    Bi, Xiao-Han
    Zhou, Hua-Fu
    JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2020, 16 (04) : 718 - 725
  • [27] Glutathione S-transferase T1 gene deletion polymorphism and lung cancer risk in Chinese population: A meta-analysis
    Wang, Yadong
    Yang, Haiyan
    Li, Li
    Wang, Haiyu
    CANCER EPIDEMIOLOGY, 2010, 34 (05) : 593 - 597
  • [28] Glutathione S-transferase P1 polymorphisms are associated with time to tumor progression in small cell lung cancer patients
    Saip, P.
    Sen, F.
    Vural, B.
    Ugurel, E.
    Demirkan, A.
    Derin, D.
    Eralp, Y.
    Camlica, H.
    Ustuner, Z.
    Ozbek, U.
    JOURNAL OF BUON, 2011, 16 (02): : 241 - 246
  • [29] Glutathione S-Transferase M1 Gene Polymorphism and Laryngeal Cancer Risk: A Meta-Analysis
    Ying, Xin-Jiang
    Dong, Pin
    Shen, Bin
    Xu, Cheng-Zhi
    Xu, Hong-Ming
    Zhao, Shu-Wei
    PLOS ONE, 2012, 7 (08):
  • [30] Glutathione S-transferase P1 Ile105Val polymorphism, cigarette smoking and prostate cancer
    Mao, GE
    Morris, G
    Lu, QY
    Cao, W
    Reuter, VE
    Cordon-Cardo, C
    Dalbagni, G
    Scher, HI
    deKernion, JB
    Zhang, ZF
    CANCER DETECTION AND PREVENTION, 2004, 28 (05): : 368 - 374
12345