Micronization of arbutine using supercritical anti-solvent

被引：0
作者：
Chan Ik Park
Moon Sam Shin
Hwayong Kim
机构：
[1] Seoul National University,School of Chemical and Biological Engineering and Institute of Chemical Processes
来源：
Korean Journal of Chemical Engineering | 2008年 / 25卷
关键词：
Arbutine; ASES; Supercritical; Anti-solvent;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Arbutine has been used as skin whitening agent in cosmetics and pharmaceuticals. The objective of this study was to precipitate arbutine micro-particles using a supercritical anti-solvent. Ethanol and supercritical CO2 were used as solvent and anti-solvent, respectively, under various conditions. The effects of pressure, temperature and solution flow rate on the particles were studied. The particle size and morphology were analyzed by field emission scanning electron microscopy.
引用
收藏
页码：581 / 584
页数：3
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