Cardiac contractility modulation therapy in advanced systolic heart failure

被引：0
作者：
Alexander R. Lyon
Michael A. Samara
David S. Feldman
机构：
[1] NIHR Cardiovascular Biomedical Research Unit,
[2] Royal Brompton Hospital,undefined
[3] Minneapolis Heart Institute,undefined
[4] Abbott Northwestern Hospital,undefined
[5] Georgia Insitute of Technology,undefined
[6] Morehouse School of Medicine,undefined
来源：
Nature Reviews Cardiology | 2013年 / 10卷
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学科分类号：
摘要：
Cardiac contractility modulation has positive inotropic effects in the failing heart, without increasing oxygen consumption. Here, Lyon and colleagues review the preclinical data, mode of action, and clinical evidence for the use of this therapy in patients with chronic heart failure. Long-term application of cardiac contractility modulation seems to improve exercise tolerance and quality of life, and have an acceptable safety profile.
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页码：584 / 598
页数：14
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