The influence of vision on tactile Hebbian learning

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作者
Esther Kuehn
Juliane Doehler
Burkhard Pleger
机构
[1] Max Planck Institute for Human Cognitive and Brain Sciences,Department of Neurology
[2] Center for Behavioral and Brain Sciences Magdeburg,Institute of Psychology
[3] Aging and Cognition Research Group,Department of Neurology
[4] DZNE,undefined
[5] Leipzig University,undefined
[6] BG University Hospital Bergmannsheil,undefined
[7] Ruhr-University Bochum,undefined
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Scientific Reports | / 7卷
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摘要
NMDA-dependent Hebbian learning drives neuronal plasticity in different cortical areas, and across species. In the primary somatosensory cortex (S-I), Hebbian learning is induced via the persistent low-rate afferent stimulation of a small area of skin. In particular, plasticity is induced in superficial cortical layers II/III of the S-I cortex that represents the stimulated area of skin. Here, we used the model system of NMDA-dependent Hebbian learning to investigate the influence of non-afferent (visual) input on Hebbian plasticity in S-I. We induced Hebbian learning in 48 participants by applying 3 hours of tactile coactivation to the right index fingertip via small loudspeaker membranes. During coactivation, different groups viewed either touches to individual fingers, which is known to activate S-I receptive fields, touches to an object, which should not activate S-I receptive fields, or no touch at all. Our results show that coactivation significantly lowers tactile spatial discrimination thresholds at the stimulated finger post- versus pre-training across groups. However, we did not find evidence for a significant modulatory effect of visual condition on tactile spatial discrimination performance. This suggests that non-afferent (visual) signals do not interact with Hebbian learning in superficial cortical layers of S-I, but may integrate into deeper cortical layers instead.
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