KRAS Mutations in Peripheral Blood (with or without CA19-9) for Differential Diagnosis of Pancreatic Cancer and Chronic Pancreatitis: a Systematic Review and Meta-analysis

被引:0
作者
Weiwei Li
Jianli Wang
Yanhua Li
Qiuju Yue
Miaohang Cui
Jinlong Liu
机构
[1] Affiliated Hospital of Chengde Medical University,Department of Hepatobiliary Surgery
[2] Kuancheng Manchu Autonomous County Hospital,General Surgery
来源
Indian Journal of Surgery | 2022年 / 84卷
关键词
CA19-9; Pancreatic cancer; Chronic pancreatitis; Diagnostic value;
D O I
暂无
中图分类号
学科分类号
摘要
Differentiation between pancreatic cancer and chronic pancreatitis remains a challenge. This meta-analysis aims to explore the diagnostic value of KRAS mutations in peripheral blood [with or without carbohydrate antigen 19–9 (CA19-9)] in pancreatic cancer and chronic pancreatitis and to discern the best method for the diagnosis of pancreatic cancer.
引用
收藏
页码:615 / 622
页数:7
相关论文
共 160 条
[1]  
Khalaf N(2021)Burden of pancreatic cancer: from epidemiology to practice Clin Gastroenterol Hepatol : Off Clin Pract J Am Gastroenterol Assoc 19 876-84
[2]  
El-Serag HB(2020)Cancer statistics, 2020 CA: Cancer J Clin 70 7-30
[3]  
Abrams HR(2014)Pancreatic adenocarcinoma New Engl J Med. 371 1039-49
[4]  
Thrift AP(2013)The clinical utility of CA 19–9 in pancreatic adenocarcinoma: diagnostic and prognostic updates Curr Mol Med. 13 340-51
[5]  
Siegel RL(2019)Impact of endoscopic ultrasonography on diagnosis of pancreatic cancer J Gastroenterol. 54 19-32
[6]  
Miller KD(2015)Methods and outcomes of screening for pancreatic adenocarcinoma in high-risk individuals World J Gastrointest Endosc. 7 833-42
[7]  
Jemal A(2020)Role of oncogenic KRAS in the diagnosis, prognosis and treatment of pancreatic cancer Nat Rev Gastroenterol Hepatol 17 153-68
[8]  
Ryan DP(2019)Clinical utility of circulating tumor DNA for colorectal cancer Cancer Sci. 110 1148-55
[9]  
Hong TS(2015)Circulating tumor cells and circulating tumor DNA: challenges and opportunities on the path to clinical utility Clin Cancer Res: Off J Am Assoc Cancer Res 21 4786-800
[10]  
Bardeesy N(2006)Low correspondence between K-ras mutations in pancreatic cancer tissue and detection of K-ras mutations in circulating DNA Pancreas. 32 171-7