Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-induced obese mice

被引:0
作者
A N A Verty
S H Lockie
A Stefanidis
B J Oldfield
机构
[1] Monash University,Department of Physiology
来源
International Journal of Obesity | 2013年 / 37卷
关键词
cannabinoids; MCH; energy expenditure; thermogenesis; lipolysis;
D O I
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中图分类号
学科分类号
摘要
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页码:279 / 287
页数:8
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[1]  
Cooke D(2006)The obesity pipeline: current strategies in the development of anti-obesity drugs Nat Rev Drug Discov 5 919-931
[2]  
Bloom S(1994)SR141716A, a potent and selective antagonist of the brain cannabinoid receptor FEBS Lett 350 240-244
[3]  
Rinaldi-Carmona M(2003)Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults N Engl J Med 348 1625-1638
[4]  
Barth F(2005)Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia N Engl J Med 353 2121-2134
[5]  
Héaulme M(2001)Leptin-regulated endocannabinoids are involved in maintaining food intake Nature 410 822-825
[6]  
Shire D(1983)Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study Circulation 67 968-977
[7]  
Calandra B(2002)Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist Nat Med 8 825-830
[8]  
Congy C(2010)The Endogenous Actions of Hypothalamic Peptides on Brown Adipose Tissue Thermogenesis in the Rat Endocrinology 151 4236-4246
[9]  
Calle EE(1998)Mice lacking melanin-concentrating hormone are hypophagic and lean Nature 396 670-674
[10]  
Rodriguez C(2005)The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance J Neurosci 25 2933-2940