Inhibition of CISD2 promotes ferroptosis through ferritinophagy-mediated ferritin turnover and regulation of p62–Keap1–NRF2 pathway

被引：0
|
作者：
Yanchun Li
Bing Xu
Xueying Ren
Luyang Wang
Yaqing Xu
Yefeng Zhao
Chen Yang
Chen Yuan
Huanjuan Li
Xiangmin Tong
Ying Wang
Jing Du
机构：
[1] Zhejiang University School of Medicine,Department of Central Laboratory, Affiliated Hangzhou First People’s Hospital
[2] Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital,Department of Clinical Laboratory, Laboratory Medicine Center
[3] Hangzhou Medical College),Department of Clinical Laboratory
[4] Hangzhou Women’s Hospital,Department of Laboratory Medicine
[5] The Second Affiliated Hospital of Zhejiang Chinese Medical University,undefined
来源：
Cellular & Molecular Biology Letters | 2022年 / 27卷
关键词：
CISD2; Iron; Autophagy; Ferroptosis; Ferritinophagy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation
    Park, Jeong Su
    Kang, Dong Hoon
    Lee, Da Hyun
    Bae, Soo Han
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 465 (03) : 542 - 547
  • [22] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
    Komatsu, Masaaki
    Kurokawa, Hirofumi
    Waguri, Satoshi
    Taguchi, Keiko
    Kobayashi, Akira
    Ichimura, Yoshinobu
    Sou, Yu-Shin
    Ueno, Izumi
    Sakamoto, Ayako
    Tong, Kit I.
    Kim, Mihee
    Nishito, Yasumasa
    Iemura, Shun-ichiro
    Natsume, Tohru
    Ueno, Takashi
    Kominami, Eiki
    Motohashi, Hozumi
    Tanaka, Keiji
    Yamamoto, Masayuki
    NATURE CELL BIOLOGY, 2010, 12 (03) : 213 - U17
  • [23] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
    Masaaki Komatsu
    Hirofumi Kurokawa
    Satoshi Waguri
    Keiko Taguchi
    Akira Kobayashi
    Yoshinobu Ichimura
    Yu-Shin Sou
    Izumi Ueno
    Ayako Sakamoto
    Kit I. Tong
    Mihee Kim
    Yasumasa Nishito
    Shun-ichiro Iemura
    Tohru Natsume
    Takashi Ueno
    Eiki Kominami
    Hozumi Motohashi
    Keiji Tanaka
    Masayuki Yamamoto
    Nature Cell Biology, 2010, 12 : 213 - 223
  • [24] Ferritinophagy-Mediated Ferroptosis and Activation of Keap1/Nrf2/HO-1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2'-Di-pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester
    Guan, Deng
    Zhou, Wei
    Wei, Huiping
    Wang, Ting
    Zheng, Kangwei
    Yang, Chunjie
    Feng, Rui
    Xu, Ruifang
    Fu, Yun
    Li, Cuiping
    Li, Yongli
    Li, Changzheng
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2022, 2022
  • [25] p62 Suppressed VK3-induced Oxidative Damage Through Keap1/Nrf2 Pathway In Human Ovarian Cancer Cells
    Xia, Mei-hui
    Yan, Xiao-yu
    Zhou, Lei
    Xu, Long
    Zhang, Li-chao
    Yi, Hao-wei
    Su, Jing
    JOURNAL OF CANCER, 2020, 11 (06): : 1299 - 1307
  • [26] A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
    Lau, Alexandria
    Wang, Xiao-Jun
    Zhao, Fei
    Villeneuve, Nicole F.
    Wu, Tongde
    Jiang, Tao
    Sun, Zheng
    White, Eileen
    Zhang, Donna D.
    MOLECULAR AND CELLULAR BIOLOGY, 2010, 30 (13) : 3275 - 3285
  • [27] MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling
    Tan, Chong Teik
    Chang, Hao-Chun
    Zhou, Qiling
    Yu, Chundong
    Fu, Nai Yang
    Sabapathy, Kanaga
    Yu, Victor C.
    EMBO REPORTS, 2021, 22 (01)
  • [28] MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling
    Tan C.T.
    Chang H.-C.
    Zhou Q.
    Yu C.
    Fu N.Y.
    Sabapathy K.
    Yu V.C.
    The EMBO Reports, 2021, 22 (1):
  • [29] Inhibition of the Keap1/Nrf2 Signaling Pathway Significantly Promotes the Progression of Type 1 Diabetes Mellitus
    Lou, Yanmei
    Kong, Muyan
    Li, Leyan
    Hu, Yu
    Zhai, Wenjun
    Qi, Xiaoxiao
    Liu, Zhongqiu
    Wu, Jinjun
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021, 2021
  • [30] hTBK1-c.978T>A mutation promotes the ferroptosis in NSC-34 cells via mediation of KEAP1/ NRF2/p62 signaling
    Zhang, Yuanjin
    Fan, Dongsheng
    Liu, Xiangyi
    Liu, Xiaolu
    He, Ji
    Zhang, Nan
    Tang, Lu
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2020, 12 (11): : 7386 - 7394
12345