Exercise-induced acute renal failure in a patient with renal hypouricemia

被引：0
|
作者：
T. Watanabe
Tokinari Abe
Yoshihiko Oda
机构：
[1] Department of Pediatrics,
[2] Niigata City General Hospital,undefined
[3] 2-6-1 Shichikuyama,undefined
[4] Niigata 950-8739,undefined
[5] Japan e-mail: twata@coral.ocn.ne.jp Tel.: +81-025-241-5151,undefined
[6] Fax: +81-025-248-3507,undefined
来源：
Pediatric Nephrology | 2000年 / 14卷
关键词：
Key words Renal hypouricemia; Acute renal failure; Urate transport;
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摘要：
We describe a case of exercise-induced acute renal failure (ARF) in a patient with hypouricemia. Following recovery from ARF, the patient’s serum urate concentration was 0.6–0.9 mg/dl, and the ratio of urate clearance to creatinine clearance (Cua/CCr) was 41.9%–56.6%. There was no change in the Cua/CCr following the administration of pyrazinamide or probenecid, suggesting defects of tubular urate/anion exchangers. Because the renal biopsy revealed acute tubular necrosis without uric acid crystals, the ARF of this patient might be due to oxygen free radicals resulting from exercise stress and hypouricemia.
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页码：851 / 852
页数：1
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