Giant Cell Arteritis and Polymyalgia Rheumatica: an Update

被引：0
作者：
Miguel A. González-Gay
Trinitario Pina
机构：
[1] IDIVAL,Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Hospital Universitario Marqués de Valdecilla
[2] University of the Witwatersrand,Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences
来源：
Current Rheumatology Reports | 2015年 / 17卷
关键词：
Giant cell arteritis; Polymyalgia rheumatica; Aortitis; FDG-PET; Treatment;
D O I：
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学科分类号：
摘要：
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two closely related diseases in people aged 50 years and older, which are more frequently observed in Western countries. Despite being common entities, concern still exists about the epidemiology, pathogenesis, and diagnosis of both entities. New imaging techniques, such as 18 fluorodeoxyglucose-positron emission tomography, have proved to be useful in detecting large-vessel involvement in GCA. Corticosteroids are the cornerstone of the therapy in GCA and PMR. Relapses are frequent in these conditions. Unlike methotrexate and tumor necrosis factor-α antagonists, anti-interleukin-6 receptor therapy appears to be useful in patients with GCA and PMR who are refractory to corticosteroids. This review summarizes recent studies on GCA and PMR.
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