Efficacy and Tolerability of Conversion from Cyclosporin to Azathioprine After Kidney TransplantationA Review of the Evidence

被引：0
作者：
Adrianus A.M.J. Hollander
Fokko J. van der Woude
机构：
[1] University Hospital,Department of Nephrology and Transplantation
[2] University of Heidelberg,Fifth Medical Clinic, Klinikum Mannheim
[3] Bosch Medicentrum,Department of Internal Medicine and Nephrology
[4] Groot Ziekengasthuis,undefined
来源：
BioDrugs | 1998年 / 9卷
关键词：
Cyclosporin; Adis International Limited; Gout; Acute Rejection; Graft Survival;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
After the introduction of cyclosporin as an immunosuppressive drug for organ transplantation at the beginning of the 1980s, concern arose about adverse effects of this new drug. Nephrotoxicity, fear of progressive loss of renal function with long term use of cyclosporin, a higher incidence of lymphomas in the first studies with cyclosporin and the high costs of the new drug led to the modification of immunosuppressive regimens so that cyclosporin was replaced by azathioprine several months after renal transplantation.
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页码：197 / 210
页数：13
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