A review of radiomics and genomics applications in cancers: the way towards precision medicine

被引：0
作者：
Simin Li
Baosen Zhou
机构：
[1] The First Hospital of China Medical University,Department of Clinical Epidemiology and Center of Evidence
来源：
Radiation Oncology | / 17卷
关键词：
Radiomics; Genomics; Cancer; Machine learning; Evidence-based medicine;
D O I：
暂无
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学科分类号：
摘要：
The application of radiogenomics in oncology has great prospects in precision medicine. Radiogenomics combines large volumes of radiomic features from medical digital images, genetic data from high-throughput sequencing, and clinical-epidemiological data into mathematical modelling. The amalgamation of radiomics and genomics provides an approach to better study the molecular mechanism of tumour pathogenesis, as well as new evidence-supporting strategies to identify the characteristics of cancer patients, make clinical decisions by predicting prognosis, and improve the development of individualized treatment guidance. In this review, we summarized recent research on radiogenomics applications in solid cancers and presented the challenges impeding the adoption of radiomics in clinical practice. More standard guidelines are required to normalize radiomics into reproducible and convincible analyses and develop it as a mature field.
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  • [1] Fernández-Lázaro D(2020)Clinical perspective and translational oncology of liquid biopsy Diagnostics (Basel) 10 E443-446
  • [2] Hernández JLG(2021)Updates on clinical use of liquid biopsy in colorectal cancer screening, diagnosis, follow-up, and treatment guidance Front Cell Dev Biol 9 441-57
  • [3] García AC(2012)Radiomics: extracting more information from medical images using advanced feature analysis Eur J Cancer 48 45-1984
  • [4] Castillo ACD(2019)Genomic medicine-progress, pitfalls, and promise Cell 177 1960-762
  • [5] Hueso MV(2021)Radiogenomics in brain, breast, and lung cancer: opportunities and challenges J Med Imaging (Bellingham) 8 749-747
  • [6] Cruz-Hernández JJ(2020)The era of radiogenomics in precision medicine: an emerging approach to support diagnosis, treatment decisions, and prognostication in oncology Front Oncol 10 732-500
  • [7] Mazouji O(2019)Radiogenomics: bridging imaging and genomics Abdom Radiol (NY) 44 E3039-1732
  • [8] Ouhajjou A(2017)Radiomics: the bridge between medical imaging and personalized medicine Nat Rev Clin Oncol 14 486-13
  • [9] Incitti R(2018)Precision medicine and radiogenomics in breast cancer: new approaches toward diagnosis and treatment Radiology 287 1717-3544
  • [10] Mansour H(2020)Radiomic immunophenotyping of GSEA-assessed immunophenotypes of glioblastoma and its implications for prognosis: a feasibility study Cancers (Basel) 12 7-331
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