In vitro and in vivo studies of99mTc IgG: A comparison between three labeling methods

被引:0
作者
M. E. Viaggi
J. Crudo
S. G. de Castiglia
机构
[1] Centro Atómico Ezeiza,Comisión Nacional de Energía Atómica
来源
Journal of Radioanalytical and Nuclear Chemistry | 1999年 / 241卷
关键词
Physical Chemistry; Inorganic Chemistry; Polyclonal Antibody; Label Method; Polyclonal Immunoglobulin;
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学科分类号
摘要
Polyclonal immunoglobulin IgG was labeled using three different methods: a direct method via 2-mercaptoethanol, an indirect one, in which a chelating group was covalently attached to the protein and the99mTc added as a glucoheptonate complex and a photoactivation method. The properties of99mTc polyclonal antibody labeled by three different methods were assessed by in vitro and in vivo studies. The ratio between inflamed thigh to normal thigh was similar and independent of the method of labeling.
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页码:173 / 177
页数:4
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