Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants

被引：0
|
作者：
Roni Rasnic
Nadav Brandes
Or Zuk
Michal Linial
机构：
[1] The Hebrew University of Jerusalem,The Rachel and Selim Benin School of Computer Science and Engineering
[2] The Hebrew University of Jerusalem,Department of Statistics
[3] The Hebrew University of Jerusalem,Department of Biological Chemistry, Institute of Life Sciences
来源：
BMC Cancer | / 19卷
关键词：
Cancer predisposition; TCGA; Germline variants; Batch effect; Somatic mutations; Personalized medicine; Next generation sequencing; BRCA1; Genomic sequencing centers;
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